2-(2-Bromophenyl)-1,3-dioxolane → Methyl 2-(1,3-dioxolan-2-yl)-phenylglyoxylate

HRID 36608

Reaction equation

HRID 36608 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]1[O:12][CH2:11][CH2:10][O:9]1.[Cl-].[CH3:14][O:15][C:16](=[O:20])[C:17](O)=[O:18]>[Zn]>[O:9]1[CH2:10][CH2:11][O:12][CH:8]1[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[C:17](=[O:18])[C:16]([O:15][CH3:14])=[O:20]

Participants

4

Reactant 2

HCID 5535342-(2-Bromophenyl)-1,3-dioxolaneHCID 86640482Oxalic acid monomethyl ester chloride

Product 1

HCID 21752929Methyl 2-(1,3-dioxolan-2-yl)-phenylglyoxylate

Reagents, catalysts & solvents 1

HCID 23994ZincCatalyst

Procedure

174.5 g of 1-bromo-2-(1,3-dioxolan-2-yl)-benzene was reacted via the zinc-organic compound with 102 g of oxalic acid monomethyl ester chloride, analogously to Example 2. Yield: 41.6 g.

Sources & evidence

ORD record
ord-b55b307c9c064234aa9707ec7ea74f53
Source dataset
uspto-grants-1995_05
Patent number
US05416068

Linked notes

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