Sodium Iodide → HCID 10988867, compound

5-Chloropentyl acetate (26.5 g, 0.16 mol) was added to a solution of sodium iodide (45 g, 0.30 mol) in dry acetone (200 ml). The resulting pale yellow solution was heated at reflux for 65 h, during which time a white solid separated (sodium chloride). The final mixture was cooled to room temperature and filtered to remove the NaCl, which was washed with acetone and diethyl ether, then dried under vacuum at 50° C. Expected yield of NaCl=9.4 g; isolated yield=9.47 g (100%).

1. temperatureThe resulting pale yellow solution was heated
2. temperatureat reflux for 65 h, during which time a white solid
3. customseparated (sodium chloride)
4. filtrationfiltered
5. customto remove the NaCl, which
6. washwas washed with acetone and diethyl ether
7. customdried under vacuum at 50° C
8. customisolated yield=9.47 g (100%)

ORD record

ord-653cf5ff72bd4a6da6bf45a68d819e95

Source dataset

uspto-grants-2000_10

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06140494