Phenacyl bromide → N-methyl-N-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenyl]benzoylmethoxyamine
Reaction equation
[C:1]([CH2:9]Br)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:11][N:12]([OH:34])[C:13]1[CH:18]=[C:17]([O:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][C:21]=2[Cl:30])[CH:16]=[CH:15][C:14]=1[N+:31]([O-:33])=[O:32]>>[CH3:11][N:12]([O:34][CH2:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[C:13]1[CH:18]=[C:17]([O:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:28])([F:27])[F:29])=[CH:22][C:21]=2[Cl:30])[CH:16]=[CH:15][C:14]=1[N+:31]([O-:33])=[O:32]Participants
3
Procedure
Following the procedure of Example 14, benzoylmethyl bromide is reacted with N-methyl-N-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenyl]hydroxyamine to give N-methyl-N-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenyl]benzoylmethoxyamine (IVA; R3 is H, n is one, and R4 is phenyl).
Sources & evidence
- ORD record
- ord-decadee382594adab8c7c8fea9e3424d
- Source dataset
- uspto-grants-1985_07