1-Hexyne → 1-(4-Bromophenyl) 2-heptyn-1-one

HRID 37203

Reaction equation

HRID 37203 reaction equation
[CH:1]#[C:2][CH2:3][CH2:4][CH2:5][CH3:6].[Br:7][C:8]1[CH:16]=[CH:15][C:11]([C:12](Cl)=[O:13])=[CH:10][CH:9]=1>C(N(CC)CC)C>[Br:7][C:8]1[CH:16]=[CH:15][C:11]([C:12](=[O:13])[C:1]#[C:2][CH2:3][CH2:4][CH2:5][CH3:6])=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 127321-HexyneHCID 685154-Bromobenzoyl chloride

Product 1

HCID 544491361-(4-Bromophenyl) 2-heptyn-1-one

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The following were stirred at ambient temperature for about 2 hours 30 minutes, 49 ml of 1-hexyne, 75 ml of triethylamine, 40 mg of cuprous iodide, 40 mg of bis triphenylphosphine palladium dichloride and 9 g of parabromobenzoyl chloride.

Sources & evidence

ORD record
ord-63ea4cacfe084abf827121e185cfa069
Source dataset
uspto-grants-1995_05
Patent number
US05420138

Linked notes

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