HCID 178449602, compound → HCID 178479356, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13]([NH:15]C(C)(C)C)=[O:14])=[NH:11]>Cl>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13]([NH2:15])=[O:14])=[NH:11]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 32.1 g. (0.106 moles) of 1-(2,6-dichlorophenylamidino)-3-(t-butyl)urea and 200 ml of conc. hydrochloric acid is refluxed for 1/2 hour. The reaction mixture is cooled, filtered and washed with 10 ml of 1:1 HCl/H2O and dried. The product is then recrystallized from ethanol-ether to obtain (2,6-dichlorophenylamidino)urea hydrochloride.
Workup
- additionA mixture of 32.1 g
- temperatureThe reaction mixture is cooled
- filtrationfiltered
- washwashed with 10 ml of 1:1 HCl/H2O
- customdried
- customThe product is then recrystallized from ethanol-ether
Sources & evidence
- ORD record
- ord-38999293618c4c159ce124ffe5460606
- Source dataset
- uspto-grants-1978_05
- Patent number
- US04088785
Reaction notes
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