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Sorbitol → Borneol-ethanol

HRID 373471
Notes
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Reaction equation

HRID 373471 reaction equation
[OH:1][CH2:2][C@@H:3]([C@H]([C@@H]([C@@H](CO)O)O)O)O.COC([C@@H](NC([C@@H](N)CC(O)=O)=O)CC1C=CC=CC=1)=O.[C:34]12([CH3:44])[C:40]([CH3:42])([CH3:41])[CH:37]([CH2:38][CH2:39]1)[CH2:36][CH:35]2[OH:43].C[C@H]1C[C@@H](O)[C@H](C(C)C)CC1>C(O)C.OCC(CO)O>[C:34]12([CH3:44])[C:40]([CH3:41])([CH3:42])[CH:37]([CH2:38][CH2:39]1)[CH2:36][C:35]2([CH2:3][CH2:2][OH:1])[OH:43]
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

7

Reactant 4

HCID 5780SorbitolHCID 16666(-)-MentholHCID 64685BorneolHCID 134601Aspartame

Product 1

HCID 21461391Borneol-ethanol

Reagents, catalysts & solvents 2

HCID 702EthanolSolvent
HCID 753
Glycerol
Solvent

Procedure

Thereafter, the warm aqueous mixture is filtered by using 100 mesh sieve and residues from the first filtration are extracted with. 20 l of water at a temperature of 80°-100° C. for 1 hour and condensed and under the reduced. Pressure to produce about 15 l of a natural substance extract. After 76.7 g of Bezoar bovis and 63.3 g of Moschus are dried on a silicagel desiccator for 24 hours and ground into microparticle size in a grinder to form a microparticle mixture by using 140 mesh sieve to make a Bezoar bovis powder and a Moschus powder, respectively. 5 Kg of conc-glycerin, 5 Kg of sugar and 35 Kg of d-sorbitol or 35 Kg of "ASPARTAME" and 10 Kg of Mel are solved with 10 l of distilled warm water for 15 minutes to make a sweetening solution. 5 l of distilled water is added to 110.0 g of genus Gelatin and the aqueous mixture is heated to produce a Gelatin solution. And 63.3 g of Borneol, and 0.5 l of L-menthol are solved with 3.5 l of ethanol to produce a Borneol-ethanol solution.

Workup

  1. filtrationThereafter, the warm aqueous mixture is filtered
  2. filtrationfrom the first filtration
  3. extractionare extracted with
  4. customcondensed
  5. customPressure to produce about 15 l of a natural substance
  6. extractionextract
  7. customAfter 76.7 g of Bezoar bovis and 63.3 g of Moschus are dried on a silicagel desiccator for 24 hours
  8. customground into microparticle size in a grinder to form a microparticle mixture
  9. distillationof distilled
  10. temperaturewarm water for 15 minutes
  11. addition5 l of distilled water is added to 110.0 g of genus Gelatin
  12. temperaturethe aqueous mixture is heated
  13. customto produce a Gelatin solution

Sources & evidence

ORD record
ord-345a2952eddb4058b36d8cb2b9dcd8f7
Source dataset
uspto-grants-1992_11
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US05164184

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes