4-Hydroxybutanal → 1,4-Butanediol

HRID 374201

Reaction equation

HRID 374201 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH:5]=[O:6].[OH:7][CH2:8][CH:9]([CH3:12])[CH:10]=[O:11]>[Pd].O1CCCC1>[CH2:5]([OH:6])[CH2:4][CH2:3][CH2:2][OH:1].[CH3:12][CH:9]([CH2:10][OH:11])[CH2:8][OH:7]

Participants

6

Reactant 2

HCID 930934-HydroxybutanalHCID 110297623-Hydroxy-2-methylpropanal

Product 2

HCID 80641,4-ButanediolHCID 75103Methylpropanediol

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

hydrogenating an aqueous solution containing 4-hydroxybutanal and 3-hydroxy-2-methylpropanal in the presence of a palladium compound supported on a zeolite-type catalyst support to produce tetrahydrofuran as the major product, and 1,4-butanediol and 2-methyl-1,3-propanediol as the minor products.

Sources & evidence

ORD record
ord-6580ae4a4ac546758697f539669a995c
Source dataset
uspto-grants-1992_11
Patent number
US05166370

Linked notes

Loading…