4-Hydroxybutanal → 1,4-Butanediol
Reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH:5]=[O:6].[OH:7][CH2:8][CH:9]([CH3:12])[CH:10]=[O:11]>[Pd].O1CCCC1>[CH2:5]([OH:6])[CH2:4][CH2:3][CH2:2][OH:1].[CH3:12][CH:9]([CH2:10][OH:11])[CH2:8][OH:7]Participants
6
Reactant 2
Product 2
Reagents, catalysts & solvents 2
Procedure
hydrogenating an aqueous solution containing 4-hydroxybutanal and 3-hydroxy-2-methylpropanal in the presence of a palladium compound supported on a zeolite-type catalyst support to produce tetrahydrofuran as the major product, and 1,4-butanediol and 2-methyl-1,3-propanediol as the minor products.
Sources & evidence
- ORD record
- ord-6580ae4a4ac546758697f539669a995c
- Source dataset
- uspto-grants-1992_11
- Patent number
- US05166370
Reaction notes
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