Propylamine → N-propyl-2-(4-nitro-1H-imidazol-1-yl) octanoamide

HRID 375114

Reaction equation

[N+:1]([C:4]1[N:5]=[CH:6][N:7]([CH:9]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:10]([O:12]CC)=O)[CH:8]=1)([O-:3])=[O:2].[CH2:21]([NH2:24])[CH2:22][CH3:23]>>[CH2:21]([NH:24][C:10](=[O:12])[CH:9]([N:7]1[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[N:5]=[CH:6]1)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:22][CH3:23]

Participants

Reactant 2

HCID 7852Propylamine

HCID 10062368Ethyl 2-(4-nitro-1H-imidazole-1-yl)octanoate

Product 1

HCID 15222340N-propyl-2-(4-nitro-1H-imidazol-1-yl) octanoamide

Procedure

Ethyl 2-(4-nitro-1H-imidazole-1-yl)octanoate (17 moles, 5.0 g) was reacted with propylamine as in Example 1 to yield 2.5 g of N-propyl-2-(4-nitro-1H-imidazol-1-yl) octanoamide. (MS).

Sources & evidence

ORD record: ord-d50b5da15aab4f31ad984ed4037e9069
Source dataset: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05484780

Linked notes

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