N,N,N',N'-Tetramethylethylenediamine → HCID 178506664, compound

HRID 37591

Reaction equation

HRID 37591 reaction equation
[CH2:1]([Li:5])[CH2:2][CH2:3][CH3:4].CN(C)CCN(C)C.[F:14][C:15]1([F:24])[O:19][C:18]2C=CC=C[C:17]=2[O:16]1>C1(C)C=CC=CC=1.CCCC>[F:14][C:15]1([F:24])[O:19][C:18]2[CH:4]=[CH:3][CH:2]=[C:1]([Li:5])[C:17]=2[O:16]1

Participants

6

Reactant 3

HCID 8037N,N,N',N'-TetramethylethylenediamineHCID 741032,2-Difluoro-1,3-benzodioxoleHCID 178418339Butyllithium

Product 1

HCID 178506664HCID 178506664, compound

Reagents, catalysts & solvents 2

HCID 1140TolueneSolventHCID 7843ButaneSolvent

Procedure

94.0 g (272 mmol) of n-butyllithium (18.5% in toluene) are added dropwise under a nitrogen atmosphere at from -15° to -10° C. to 29.5 g (254 mmol) of N,N,N',N'-tetramethylethylenediamine and 40.0 g (253 mmol) of 2,2-difluoro-1,3-benzodioxole in 35 ml of toluene, n-butane being formed in addition to the title compound.

Sources & evidence

ORD record
ord-44b8767689f24a01ab6b681b7cf23085
Source dataset
uspto-grants-1995_05
Patent number
US05420301

Linked notes

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