4-Nitrobenzyl chloride → HCID 19357861, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[CH2:16][S:15][C:14](=[O:17])[NH:13][N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[N+:18]([C:21]1[CH:28]=[CH:27][C:24]([CH2:25]Cl)=[CH:23][CH:22]=1)([O-:20])=[O:19]>>[N+:18]([C:21]1[CH:28]=[CH:27][C:24]([CH2:25][N:13]2[N:12]=[C:11]([C:5]3[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH2:16][S:15][C:14]2=[O:17])=[CH:23][CH:22]=1)([O-:20])=[O:19]Participants
3
Procedure
In analogy to Example 1, the reaction of 5-(3,4-dimethoxyphenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one ("B") with 4-nitrobenzyl chloride gives 3-(4-nitrobenzyl)-5-(3,4-dimethoxyphenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one, m.p. 155°.
Sources & evidence
- ORD record
- ord-5088e728f5394cb98f3f20b437d97245
- Source dataset
- uspto-grants-2000_02
- Patent number
- US06025354