3(2H)-Pyridazinone → 6-(4-iodophenyl)pyridazin-3(2H)-one
Reaction equation
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([I:10])=[CH:6][CH:5]=1)=O.[N:11]1[NH:12][C:13](=[O:17])[CH:14]=CC=1>>[I:10][C:7]1[CH:8]=[CH:9][C:4]([C:2]2[CH:1]=[CH:14][C:13](=[O:17])[NH:12][N:11]=2)=[CH:5][CH:6]=1Participants
3
Procedure
7.8 g of 4-iodoacetophenone are converted into the pyridazinone in accordance with GWP 1.
Sources & evidence
- ORD record
- ord-e51a63ad887e43438f2b6e7dc1efd022
- Source dataset
- uspto-grants-2013_02
- Patent number
- US08367668B2
Reaction notes
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