Tetrahydro-4H-pyran-4-ol → 4-(4-Bromo-3-fluoro-phenoxy)-tetrahydro-pyran

HRID 384890

Reaction equation

HRID 384890 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[F:9].[O:10]1[CH2:15][CH2:14][CH:13](O)[CH2:12][CH2:11]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH:13]2[CH2:14][CH2:15][O:10][CH2:11][CH2:12]2)=[CH:4][C:3]=1[F:9]

Participants

3

Reactant 2

HCID 74956Tetrahydro-4H-pyran-4-olHCID 27791534-Bromo-3-fluorophenol

Product 1

HCID 652029954-(4-Bromo-3-fluoro-phenoxy)-tetrahydro-pyran

Procedure

The title compound was prepared from 4-bromo-3-fluorophenol and tetrahydro-4H-pyran-4-ol in analogy to Example 9c): MS (EI): 274 and 276 M+.

Sources & evidence

ORD record
ord-1d83e4752ec546d3a0519722c104fb32
Source dataset
uspto-grants-2013_02
Patent number
US08367838B2

Linked notes

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