1-Octanol → Carbamic acid, octyl ester

HRID 402963

Reaction equation

HRID 402963 reaction equation
[CH2:1]([OH:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[NH2:10][C:11](N)=[O:12]>>[C:11](=[O:12])([O:9][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[NH2:10]

Participants

3

Reactant 2

HCID 9571-OctanolHCID 1176Urea3×

Product 1

HCID 16240Carbamic acid, octyl ester

Procedure

A 1000 mL glass flask equipped with a reflux condenser, a gas-liquid separator, and a stirrer was charged with 522.4 g (4.01 mol) of 1-octanol and 60.07 g (1.00 mol) of urea. While the mixture was stirred at 500 rpm and nitrogen gas was allowed to flow at 30 mL per minute, the mixture was allowed to react at 165° C. After 90 min, 52.1 g (0.87 mol) of urea was added, and after 120 min, 49.34 g (0.82 mol) of urea was added, and the mixture was allowed to react at a reaction temperature of 165° C.

Workup

  1. customA 1000 mL glass flask equipped with a reflux condenser
  2. customto react at 165° C
  3. waitafter 120 min
  4. customto react at a reaction temperature of 165° C.

Sources & evidence

ORD record
ord-78c9172d352b4deeba4e0094df9a5f27
Source dataset
uspto-grants-2014_06
Patent number
US08742164B2

Linked notes

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