HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 40581Generated: October 26, 2026
1,4-Dioxane → 6-Chloroquinoline-2-carbaldehyde
https://huagongshe.com/reaction/40581
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 6-Chloroquinaldine | HCID 135965 | — |
| Product | 6-Chloroquinoline-2-carbaldehyde | HCID 271283 | — |
Reaction Steps
A suspension of 6-chloro-2-methyl-quinoline (355 mg) and SeO2 (233 mg) in 1,4-dioxane (3 mL) was heated at 80° C. for 16 h. The resulting black mixture was filtered through diatomaceous earth. Concentration of the filtrate gave the title compound as a yellow powder (324 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08530476B2 |
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| Source dataset | uspto-grants-2013_09 |
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| ORD ID | ord-2952c511f0834aa6ab9efb4ef46915e5 |
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| Source note | uspto-grants-2013_09 |
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