Magnesium Stearate → HCID 178484382, compound

HRID 408059

Reaction equation

HRID 408059 reaction equation
[CH3:1][N:2]([C:4]([N:6]=[C:7]([NH2:9])[NH2:8])=[NH:5])[CH3:3].Cl.C([O-])(=O)CCCCCCCCCCCCCCCCC.[Mg+2].C([O-])(=O)CCCCCCCCCCCCCCCCC>O>[CH3:1][N:2]([C:4]([NH:6][C:7]([NH2:9])=[NH:8])=[NH:5])[CH3:3]

Participants

4

Reactant 2

HCID 11177Magnesium StearateHCID 14219Metformin Hydrochloride2×

Product 1

HCID 178484382HCID 178484382, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Metformin hydrochloride is screened through 1 mm sieve. Screened metformin hydrochloride and hydroxypropylmethylcellulose are granulated in fluid bed granulator with demineralized water and dried in the same device. Dried granulate is screened through 1 mm sieve. Obtained granulate and microcrystalline cellulose are homogenously blended in a bin blender. Pre-sieved magnesium stearate is added to the obtained blend and blended in a bin blender so that the final blend is obtained.

Workup

  1. customdried in the same device
  2. customDried granulate
  3. customObtained granulate
  4. customis obtained

Sources & evidence

ORD record
ord-70c38b47b1a94e53bad12dae7a19f7b3
Source dataset
uspto-grants-2014_06
Patent number
US08758815B2

Linked notes

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