Hydrochloric Acid → HCID 178479231, compound

Reaction equation

C([NH:8][CH2:9][C@H:10]1[CH2:15][CH2:14][C@H:13]([OH:16])[CH2:12][CH2:11]1)(OC(C)(C)C)=O.[ClH:17]>>[ClH:17].[NH2:8][CH2:9][C@H:10]1[CH2:15][CH2:14][C@H:13]([OH:16])[CH2:12][CH2:11]1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 178453650HCID 178453650, compound

Product 1

HCID 178479231HCID 178479231, compound

Procedure

trans-4-Aminomethyl-cyclohexanol hydrochloride (342 mg) was prepared by following General Procedure L using trans-N-Boc-4-aminomethyl-cyclohexanol (500 mg) and hydrogen chloride (5.45 mL, 4.0 M solution in 1,4-dioxane).

Sources & evidence

ORD record: ord-0e1cf77a4fad4c6580bca539a72c3a4b
Source dataset: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08759535B2

Reaction notes

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