Trifluoroacetic acid → 4-Chloro-2-[2-(dimethylamino)-2-oxoethoxy]-N-[2-(1-piperazinyl)ethyl]benzamide trifluoroacetate
Reaction equation
[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]([NH:8][CH2:9][CH2:10][N:11]2[CH2:16][CH2:15][N:14](C(OC(C)(C)C)=O)[CH2:13][CH2:12]2)=[O:7])=[C:4]([O:26][CH2:27][C:28]([N:30]([CH3:32])[CH3:31])=[O:29])[CH:3]=1.[F:33][C:34]([F:39])([F:38])[C:35]([OH:37])=[O:36]>ClCCl>[F:33][C:34]([F:39])([F:38])[C:35]([OH:37])=[O:36].[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]([NH:8][CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)=[O:7])=[C:4]([O:26][CH2:27][C:28]([N:30]([CH3:32])[CH3:31])=[O:29])[CH:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The product of step (c) (0.55 g) was dissolved in dichloromethane (15 ml) and trifluoroacetic acid (3 ml) added. After 1 hour the solvent was evaporated and the product obtained as a solid (0.9 g), m.p. 120-122° C.