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tert-Butyl 2-(5-chloro-6-phenylpyridin-3-ylamino)-5-methylbenzoate → HCID 25186718, compound

HRID 42060
Notes
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Reaction equation

HRID 42060 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:14][C:15]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][C:16]=2[C:17]([O:19]C(C)(C)C)=[O:18])[CH:5]=[N:6][C:7]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(O)(C(F)(F)F)=O>[Cl:1][C:2]1[CH:3]=[C:4]([NH:14][C:15]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][C:16]=2[C:17]([OH:19])=[O:18])[CH:5]=[N:6][C:7]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

3

Reactant 1

HCID 86657263tert-Butyl 2-(5-chloro-6-phenylpyridin-3-ylamino)-5-methylbenzoate

Product 1

HCID 25186718HCID 25186718, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Obtained (0.005 g, 87% of yield) following the procedure described in Example 8 (step B) starting with 0.006 g (0.02 mmol) of tert-Butyl 2-(5-chloro-6-phenylpyridin-3-ylamino)-5-methylbenzoate in 1 ml of TFA.

Workup

  1. customObtained
  2. custom(0.005 g, 87% of yield)

Sources & evidence

ORD record
ord-90ce822ad7ce44f6b939fadafdf54175
Source dataset
uspto-grants-2013_09
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US08536165B2

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes