HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 2-Amino-4-beta-hydroxyethylamino-5-chloronitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 4,5-Dichloro-2-nitroaniline | HCID 81149 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Amino-4-beta-hydroxyethylamino-5-chloronitrobenzene | HCID 53727137 | — |
Reaction Steps
0.11 mole (22.8 g) of 4,5-dichloro-2-nitroaniline is added to a solution of 0.55 mole (33.3 ml) of ethanolamine in 70 ml of dioxane. The reaction mixture is heated for 6 hours in refluxing dioxane. After dilution with water and neutralization with concentrated hydrochloric acid, the expected product precipitates.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04725283 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-b1ae56670021489c8b0a911be0cc61d1 |
| Source note | uspto-grants-1988_02 |