Pyrrolidine → [4'-(3-Chloropropoxy)[1,1'-biphenyl]-4-yl](pyrrolidin-1-yl)methanone

HRID 429240

Reaction equation

HRID 429240 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18](Cl)=[O:19])=[CH:14][CH:13]=2)=[CH:8][CH:7]=1.[NH:21]1[CH2:25][CH2:24][CH2:23][CH2:22]1>>[Cl:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([N:21]3[CH2:25][CH2:24][CH2:23][CH2:22]3)=[O:19])=[CH:14][CH:13]=2)=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 183547664'-(3-Chloropropoxy)[1,1'-biphenyl]-4-carbonyl chloride

Product 1

HCID 22994486[4'-(3-Chloropropoxy)[1,1'-biphenyl]-4-yl](pyrrolidin-1-yl)methanone

Procedure

The product from Example 10D and pyrrolidine were processed as described in Example 10E to provide the title compound.

Sources & evidence

ORD record
ord-0f0e760d354c462f801bcd33a813e5ec
Source dataset
uspto-grants-2001_11
Patent number
US06316475B1

Linked notes

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