Sodium Ascorbate → 2-keto-L-Gulonic acid

HRID 429999

Reaction equation

HRID 429999 reaction equation
[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([OH:6])=[C:3]1[OH:4].[O:13]=C1O[C@H]([C@H](CO)O)C([O-])=C1O.[Na+]>CO>[CH2:11]([OH:12])[C@H:9]([OH:10])[C@@H:7]([OH:13])[C@H:5]([OH:6])[C:3]([C:2]([OH:8])=[O:1])=[O:4]

Participants

4

Reactant 2

HCID 23667548Sodium AscorbateHCID 54670067L-Ascorbic Acid

Product 1

HCID 1024242-keto-L-Gulonic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In particular, the process of the invention may be applied to a methanolic solution of ascorbic acid or sodium ascorbate produced by esterification of 2-keto-L-gulonic acid in methanol, followed by cyclization with sodium bicarbonate to produce a feed composition to the solvent exchanger to produce an aqueous product of ascorbic acid or sodium ascorbate. The product may then be obtained from the aqueous stream by crystallization.

Sources & evidence

ORD record
ord-f81303e314574d8ba5ca89cd37ecef26
Source dataset
uspto-grants-2001_11
Patent number
US06320061B1

Linked notes

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