Camp → Camp

HRID 435452

Reaction equation

HRID 435452 reaction equation
[CH:1]1[N:2]=[C:3]([NH2:22])[C:4]2[N:9]=[CH:8][N:7]([C@@H:10]3[O:14][C@@H:13]4[CH2:15][O:16][P:17]([OH:20])([O:19][C@H:12]4[C@H:11]3[OH:21])=[O:18])[C:5]=2[N:6]=1.[CH2:23]([N:27]([CH2:32][CH2:33][CH2:34][CH3:35])[CH2:28][CH2:29][CH2:30][CH3:31])[CH2:24][CH2:25][CH3:26]>O.C(O)C>[CH2:32]([NH+:27]([CH2:23][CH2:24][CH2:25][CH3:26])[CH2:28][CH2:29][CH2:30][CH3:31])[CH2:33][CH2:34][CH3:35].[CH:1]1[N:2]=[C:3]([NH2:22])[C:4]2[N:9]=[CH:8][N:7]([C@@H:10]3[O:14][C@@H:13]4[CH2:15][O:16][P:17]([OH:20])([O:19][C@H:12]4[C@H:11]3[OH:21])=[O:18])[C:5]=2[N:6]=1

Participants

6

Reactant 2

HCID 6076CampHCID 7622Tributylamine

Product 2

HCID 6076CampHCID 3724478Tributylammonium

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

One gram of cAMP was dissolved in a mixture of 5 ml of water, 5 ml of ethanol and 1.5 ml of tri-n-butylamine. The solution was concentrated under reduced pressure at 30° to 40° C., and dried under reduced pressure using phosphorus pentoxide to afford tri-n-butylammonium salt of cAMP. The resulting cAMP salt was dissolved in 50 ml of dehydrated dimethyl formamide, and 5 ml of tri-n-butylamine and 2 ml of ethyl iodide were added. The reaction was performed at 80° C. for 3 hours.

Workup

  1. concentrationThe solution was concentrated under reduced pressure at 30° to 40° C.
  2. customdried under reduced pressure

Sources & evidence

ORD record
ord-aaf50001b54648159f4890dd51ca7ddd
Source dataset
uspto-grants-1983_08
Patent number
US04401808

Linked notes

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