Sodium Chloride → Thyroxine

HRID 435515

Reaction equation

HRID 435515 reaction equation
C(O[NH:6][C@H:7]([C:27]([OH:29])=[O:28])[CH2:8][C:9]1[CH:16]=[C:14]([I:15])[C:13]([O:17][C:18]2[CH:25]=[C:23]([I:24])[C:22]([OH:26])=[C:20]([I:21])[CH:19]=2)=[C:11]([I:12])[CH:10]=1)(C)(C)C.[Na+].[Cl-]>P([O-])([O-])([O-])=O.[K+].[K+].[K+]>[NH2:6][C@H:7]([C:27]([OH:29])=[O:28])[CH2:8][C:9]1[CH:10]=[C:11]([I:12])[C:13]([O:17][C:18]2[CH:19]=[C:20]([I:21])[C:22]([OH:26])=[C:23]([I:24])[CH:25]=2)=[C:14]([I:15])[CH:16]=1

Participants

4

Reactant 2

HCID 5234Sodium ChlorideHCID 54358334N-(tert-butoxy)-L-thyroxine

Product 1

HCID 5819Thyroxine

Reagents, catalysts & solvents 1

HCID 62657Potassium Phosphate, TribasicSolvent

Procedure

30 mg of N-(tert-butoxy)-L-thyroxine-catalase conjugate (10 mL of 3.0 mg/mL solution in 10 mM potassium phosphate buffer, pH 7) is attached to the latex polymer particles prepared according to Example 1, particle size 0.069 μm, following the procedure of Example 7 except that the reaction is performed at 40° C. in the absence of NaCl.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-6633a581c29646fc851e0d2711a89ced
Source dataset
uspto-grants-1983_08
Patent number
US04401765

Linked notes

Loading…