Cycloheptylamine → HCID 12671225, compound
Reaction equation
Cl[C:2]1[N:7]2[N:8]=[CH:9][N:10]=[C:6]2[N:5]=[C:4]([CH3:11])[C:3]=1[CH2:12][CH2:13]Cl.[CH:15]1([NH2:22])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1.C(N(CC)CC)C>C(O)C>[CH:15]1([N:22]2[C:2]3[N:7]4[N:8]=[CH:9][N:10]=[C:6]4[N:5]=[C:4]([CH3:11])[C:3]=3[CH2:12][CH2:13]2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 2g of 7-chloro-6-(2-chloroethyl)-5-methyl-s-triazolo[1,5-a]pyrimidine, 0.98g of cycloheptylamine, 3 ml of triethylamine and 20 ml of ethanol was stirred under reflux for 1.5 hours and treated thereafter as described in Example 5. The crystals thus obtained were crystallized from tetrahydrofuranisopropyl ether to give 1.4g of pale yellow needles of m.p. 197° - 198° C.