Potassium Hydroxide → HCID 21452975, compound

HRID 436640

Reaction equation

HRID 436640 reaction equation
[F:1][C:2]([F:14])([F:13])[O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8](Cl)=[O:9])=[CH:6][CH:5]=1.[CH2:15]([NH2:24])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][NH2:23].[OH-:25].[K+]>C(Cl)CCl>[F:1][C:2]([F:14])([F:13])[O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][NH:24][C:8](=[O:9])[C:7]2[CH:11]=[CH:12][C:4]([O:25][C:2]([F:1])([F:13])[F:14])=[CH:5][CH:6]=2)=[O:9])=[CH:6][CH:5]=1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 242501,8-OctanediamineHCID 1421104-(Trifluoromethoxy)benzoyl Chloride

Product 1

HCID 21452975HCID 21452975, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

m.p. 164°-165° C., 12.0 g., was prepared as in Example 16 using 4-trifluoromethoxybenzoyl chloride (from 16.5 g. of 4-trifuoromethoxybenzoic acid as in Example 16) in 150 ml. of ethylene dichloride, 7.2 g. of 1,8-octanediamine, 200 ml. of 10% aqueous potassium hydroxide solution, 500 ml. of ethylene dichloride and recrystallization from methanol using decolorizing charcoal.

Workup

  1. customof ethylene dichloride and recrystallization from methanol using

Sources & evidence

ORD record
ord-4328c9115ca741f790597127e260cedf
Source dataset
uspto-grants-1977_02
Patent number
US04009208

Linked notes

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