Benzaldehyde → 1-Acetyl-2-(4-benzalaminophenyl)hydrazine

HRID 437502

Reaction equation

HRID 437502 reaction equation
[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1)(=[O:3])[CH3:2].[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)C>[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]=[CH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 81068Acetic acid, 2-(4-aminophenyl)hydrazide

Product 1

HCID 214278361-Acetyl-2-(4-benzalaminophenyl)hydrazine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
75 °C

Procedure

1-Acetyl-2-(4-aminophenyl)hydrazine (8.25 g, 0.05 mole) and benzaldehyde (5.3 g, 0.05 mole) were mixed in ethanol (50 ml). The mixture was stirred thoroughly and was warmed to approximately 75° C for one-half hour. The addition product precipitated out of the reaction mixture. The mixture was chilled in ice and then filtered. The solid was washed with ether and dried. The product was a white cyrstalline powder. Yield 12.0 g (94%), m.p. 172°-174° C.

Workup

  1. customThe addition product precipitated out of the reaction mixture
  2. temperatureThe mixture was chilled in ice
  3. filtrationfiltered
  4. washThe solid was washed with ether
  5. customdried

Sources & evidence

ORD record
ord-d49fefbf4b7347228e14f9c3109f4efe
Source dataset
uspto-grants-1977_06
Patent number
US04031127

Linked notes

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