Methyl iodide → HCID 10485970, compound

HRID 443173

Reaction equation

HRID 443173 reaction equation
[CH2:1]([N:19]([CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH3:55])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:56][I:57]>C1COCC1>[I-:57].[CH3:56][N+:19]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH3:55]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 458429Trioctadecylamine

Product 1

HCID 10485970HCID 10485970, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

N-(3β-cholestanyl)-N-methyl-N,N-dioctadecylammonium chloride of the formula (VIII): ##STR16## The gelators of Examples VI-IX are synthesized by the following procedures. N-methyl-N,N,N-trioctadecylammonium iodide is prepared according to the following process. 0.10 g (0.13 mmol) trioctadecylamine is dissolved in 1.5 ml THF (certified grade, Fisher), and 0.1 ml (1.6 mmol) CH3I (99%, Aldrich) is placed in the above solution. The solution is stirred in a nitrogen atmosphere at 38°-40° C. for 3 h. 95 mg (80%) white solid, mp 108°-111° C., is obtained after the solvent is evaporated under house vacuum pressure, and the residue is recrystallized in ethanol (anhydrous). IR (KBr) 2917, 2859 (C-H stretching, vvs), 1473 (C-H bending, w) cm-1. 1HNMR (CDCl3) δ 3.52-3.38 (CH2, m, 6H), 3.31 (CH3, s, 3H), 1.76-0.82 (heptadecyl groups, m, 105H).

Sources & evidence

ORD record
ord-9a00909e838746b6991426c83bac4f62
Source dataset
uspto-grants-1999_04
Patent number
US05892116

Linked notes

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