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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 443519Generated: October 27, 2026

4-Amino-1,2,4-triazole → 8-(3-Thienyl)-1,2,4-triazolo[4,3-b]pyridazine

https://huagongshe.com/reaction/443519

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-1,2,4-triazoleHCID 11432—
Reactant3-Dimethylamino-1-thien-3-ylpropen-1-oneHCID 596466—
SolventO-XyleneHCID 7237—
Product8-(3-Thienyl)-1,2,4-triazolo[4,3-b]pyridazineHCID 23467593—

Reaction Steps

As for Example 16, a mixture of 3-dimethylamino-1-(3-thienyl)-2-propen-1-one, 4-amino-1,2,4-triazole and xylene is refluxed for 16 hours to give the product of the Example.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04260756
Source datasetuspto-grants-1981_04
ORD IDord-cca759562e854a6ca181c33379774f96
Source noteuspto-grants-1981_04