4-Amino-1,2,4-triazole → 8-(2-Pyridyl)-1,2,4-triazolo[4,3-b]pyridazine
Reaction equation
C[N:2](C)[CH:3]=[CH:4][C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=1)=O.N[N:15]1[CH:19]=[N:18][N:17]=[CH:16]1>C1(C)C(C)=CC=CC=1>[N:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[C:5]1[C:19]2[N:15]([CH:16]=[N:17][N:18]=2)[N:2]=[CH:3][CH:4]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
As for Example 16, a mixture of 3-dimethylamino-1-(2-pyridyl)-2-propen-1-one, 4-amino-1,2,4-triazole and xylene is refluxed for 16 hours to give the product of the Example.
Workup
- temperatureis refluxed for 16 hours
- customto give the product of the Example
Sources & evidence
- ORD record
- ord-aebb5e9a5cc14393b4f4245b6d4c5e7b
- Source dataset
- uspto-grants-1981_04
- Patent number
- US04260756
Reaction notes
Loading…