4-Amino-1,2,4-triazole → 8-(2-Pyridyl)-1,2,4-triazolo[4,3-b]pyridazine

HRID 443520

Reaction equation

HRID 443520 reaction equation
C[N:2](C)[CH:3]=[CH:4][C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=1)=O.N[N:15]1[CH:19]=[N:18][N:17]=[CH:16]1>C1(C)C(C)=CC=CC=1>[N:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[C:5]1[C:19]2[N:15]([CH:16]=[N:17][N:18]=2)[N:2]=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 114324-Amino-1,2,4-triazoleHCID 5669933-Dimethylamino-1-(2-pyridyl)prop-2-en-1-one

Product 1

HCID 234675758-(2-Pyridyl)-1,2,4-triazolo[4,3-b]pyridazine

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

As for Example 16, a mixture of 3-dimethylamino-1-(2-pyridyl)-2-propen-1-one, 4-amino-1,2,4-triazole and xylene is refluxed for 16 hours to give the product of the Example.

Workup

  1. temperatureis refluxed for 16 hours
  2. customto give the product of the Example

Sources & evidence

ORD record
ord-aebb5e9a5cc14393b4f4245b6d4c5e7b
Source dataset
uspto-grants-1981_04
Patent number
US04260756

Linked notes

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