Dichloromethane → 2-(2-Naphthyloxy)ethyl methanesulfonate

HRID 443636Notes

Reaction equation

HRID 443636 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][CH2:12][CH2:13][OH:14].ClCCl.[CH3:18][S:19](Cl)(=[O:21])=[O:20]>C(N(CC)CC)C>[CH3:18][S:19]([O:14][CH2:13][CH2:12][O:11][C:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1)(=[O:21])=[O:20]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 71312-(2-Naphthoxy)ethanolHCID 31297Methanesulfonyl chloride

Product 1

HCID 190043832-(2-Naphthyloxy)ethyl methanesulfonate

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

As described in Example 2, 13.5 g. of 2-(2-naphthyloxy)ethanol in 400 ml. of dichloromethane is reacted with 9.5 g. of methanesulfonyl chloride in the presence of 11.4 g. of triethylamine to give the product as tan crystals.

Sources & evidence

ORD record
ord-e0de3a90955d439684568c996684aa72
Source dataset
uspto-grants-1981_04
Patent number
US04260816

Reaction notes

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