2-Phenyl-1-propanol → 4-(2-Fluoro-1-methyl-ethyl)-benzenesulfonyl chloride

HRID 450712

Reaction equation

HRID 450712 reaction equation
[F:1][CH2:2][C@H:3]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([Cl:14])(=[O:13])=[O:12])=[CH:7][CH:6]=1)[CH3:4].C1(C(C)CO)C=CC=CC=1>>[F:1][CH2:2][CH:3]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([Cl:14])(=[O:12])=[O:13])=[CH:9][CH:10]=1)[CH3:4]

Participants

3

Reactant 2

HCID 142952-Phenyl-1-propanolHCID 536286004-((S)-2-Fluoro-1-methyl-ethyl)-benzenesulfonyl chloride

Product 1

HCID 536286044-(2-Fluoro-1-methyl-ethyl)-benzenesulfonyl chloride

Procedure

Following the procedures analogous to that used for the preparation of 4-((S)-2-fluoro-1-methyl-ethyl)-benzenesulfonyl chloride, but starting with 2-phenyl-1-propanol in step a.3.1, the title compound was prepared.

Sources & evidence

ORD record
ord-bfbeb2d7e3014e2fa8bd46932620f100
Source dataset
uspto-grants-2013_07
Patent number
US08486984B2

Linked notes

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