3-Chlorophenol → [3-(4-Bromo-phenyl)-3-(3-chloro-phenoxy)-propyl]chloride

HRID 45528

Reaction equation

HRID 45528 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.[Br:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16](O)[CH2:17][CH2:18][Cl:19])=[CH:12][CH:11]=1>>[Br:9][C:10]1[CH:11]=[CH:12][C:13]([CH:16]([O:8][C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[CH2:17][CH2:18][Cl:19])=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 79333-ChlorophenolHCID 108006384-Bromo-alpha-(2-chloroethyl)benzenemethanol

Product 1

HCID 59331930[3-(4-Bromo-phenyl)-3-(3-chloro-phenoxy)-propyl]chloride

Procedure

3-Chlorophenol was reacted with 1-(4-Bromo-phenyl)-3-chloro-propan-1-ol following the procedure set out in Example 48B to give the title compound, which was used in the next step without further purification.

Sources & evidence

ORD record
ord-c5554c5244af456e8923b35b7d1aaf26
Source dataset
uspto-grants-2013_09
Patent number
US08541461B2

Linked notes

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