Bromoacetyl bromide → N-Benzo[1,3]dioxol-5-ylmethyl-2-[1-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-acetamide
Reaction equation
Br[CH2:2][C:3](Br)=[O:4].[CH2:6]([NH2:16])[C:7]1[CH:15]=[CH:14][C:13]2[O:12][CH2:11][O:10][C:9]=2[CH:8]=1.[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH:38]=[CH:39][C:40]=1[O:41][CH3:42])[CH2:22][CH:23]1[C:29]2[CH:30]=[C:31]([O:36][CH3:37])[C:32]([O:34][CH3:35])=[CH:33][C:28]=2[CH2:27][CH2:26][CH2:25][NH:24]1>>[O:12]1[C:13]2[CH:14]=[CH:15][C:7]([CH2:6][NH:16][C:3](=[O:4])[CH2:2][N:24]3[CH2:25][CH2:26][CH2:27][C:28]4[CH:33]=[C:32]([O:34][CH3:35])[C:31]([O:36][CH3:37])=[CH:30][C:29]=4[CH:23]3[CH2:22][C:21]3[CH:38]=[CH:39][C:40]([O:41][CH3:42])=[C:19]([O:18][CH3:17])[CH:20]=3)=[CH:8][C:9]=2[O:10][CH2:11]1Participants
4
Reactant 3
Product 1
Procedure
prepared by reaction of 2-bromoacetyl bromide with piperonylamine and 1-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepine.