HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-4'-hydroxybenzophenone → (2S)-3-(4-{3-[4-(4-Fluoro-benzoyl)-phenoxy]-prop-1-ynyl}-phenyl)-2-methoxy-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-4'-hydroxybenzophenone | HCID 117666 | — |
| Reactant | (2S)-3-[4-(3-Chloro-prop-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester | HCID 58822943 | — |
| Product | (2S)-3-(4-{3-[4-(4-Fluoro-benzoyl)-phenoxy]-prop-1-ynyl}-phenyl)-2-methoxy-propionic acid | HCID 58822979 | — |
Reaction Steps
The title compound was prepared from (2S)-3-[4-(3-Chloro-prop-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 5, Step A and 4-fluoro-4′-hydroxybenzophenone in a manner analogous to that described for Example 5, Step B. MS(ES) for C26H21FO[M+H]+: 433.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-c10001cf943742afbaaed7f0e773fc7d |
| Source note | uspto-grants-2007_03 |