N,N'-Diethylthiourea → 3-Ethyl-2-ethylimino-4-(2,4-dichloro-5-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrobromide

HRID 460820

Reaction equation

HRID 460820 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]([Cl:15])=[CH:7][C:6]=1[Cl:16])=[O:4].[CH2:17]([NH:19][C:20]([NH:22][CH2:23][CH3:24])=[S:21])[CH3:18]>>[BrH:1].[CH2:23]([N:22]1[C:3]([C:5]2[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]([Cl:15])=[CH:7][C:6]=2[Cl:16])([OH:4])[CH2:2][S:21][C:20]1=[N:19][CH2:17][CH3:18])[CH3:24]

Participants

3

Reactant 2

HCID 2735009N,N'-DiethylthioureaHCID 227564292-Bromo-2',4'-dichloro-5'-sulfamoylacetophenone

Product 1

HCID 213947703-Ethyl-2-ethylimino-4-(2,4-dichloro-5-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrobromide

Procedure

was obtained in a manner analogous to that described in Example 1 d) from 3.5 g of 2-bromo-2',4'-dichloro-5'-sulfamoyl-acetophenone and 1.3 g of 1,3-diethyl-thiourea. M.p. 202° C (decomposition).

Workup

  1. customwas obtained in a manner analogous to
  2. customthat described in Example 1 d

Sources & evidence

ORD record
ord-0cddd439074d4f16a1cd7714e865d04f
Source dataset
uspto-grants-1977_12
Patent number
US04061647

Linked notes

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