HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylthiourea → 4-(2,4-Dichloro-5-sulfamoylphenyl)-3-cyclohexyl-2-cyclohexylimino-1,3-thiazolidine-4-ol-hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylthiourea | HCID 727200 | — |
| Reactant | 2-Bromo-2',4'-dichloro-5'-sulfamoylacetophenone | HCID 22756429 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(2,4-Dichloro-5-sulfamoylphenyl)-3-cyclohexyl-2-cyclohexylimino-1,3-thiazolidine-4-ol-hydrobromide | HCID 21394764 | — |
Reaction Steps
2.4 g of 1,3-dicyclohexyl-thiourea were added to 3,5 g of 2-bromo-2',4'-dichloro-5'-sulfamoylacetophenone in 40 ml of ethyl acetate. The whole was allowed to stand overnight at 20° C, the crystals were filtered off and washed with ethyl acetate. M.p. 161°-163° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061647 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-208c8c3e928e44cca51f415e62697259 |
| Source note | uspto-grants-1977_12 |