Phosphoric Acid → L-ornithine hydrofluoride phosphate

HRID 461676

Reaction equation

HRID 461676 reaction equation
[FH:1].[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH2:5][CH2:6][NH2:7].[P:11](=[O:15])([OH:14])([OH:13])[OH:12]>>[P:11]([OH:15])([OH:14])([OH:13])=[O:12].[FH:1].[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH2:5][CH2:6][NH2:7]

Participants

4

Reactant 3

HCID 1004Phosphoric AcidHCID 6262L-(-)-OrnithineHCID 14917Hydrofluoric Acid

Product 1

HCID 86735289L-ornithine hydrofluoride phosphate

Procedure

L-ornithine hydrofluoride phosphate was prepared by adding 0.1 mole hydrofluoric acid to 0.1 mole free base ornithine and then adding 0.1 mole of orthophosphoric acid. The resulting solution was concentrated in a vacuum evaporator and poured into 350 ml. of a methanol-ethanol mixture. A gummy precipitate resulted. The precipitate was then dried over calcium chloride in a desiccator. The product was L-ornithine hydrofluoride phosphate.

Workup

  1. concentrationThe resulting solution was concentrated in a vacuum evaporator
  2. additionpoured into 350 ml
  3. customA gummy precipitate resulted
  4. dry with materialThe precipitate was then dried over calcium chloride in a desiccator

Sources & evidence

ORD record
ord-5613025de35a407abd215ddf86e25c37
Source dataset
uspto-grants-1977_12
Patent number
US04064138

Linked notes

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