Hydrochloric Acid → N-Acetyl-3,4-dimethoxyphenethylamine

HRID 462104

Reaction equation

Cl.ClC[C:4]1[C:9]([CH2:10][CH2:11][NH:12][C:13](=[O:15])[CH3:14])=[CH:8][C:7]([O:16][CH3:17])=[C:6]([O:18][CH3:19])[CH:5]=1>>[C:13]([NH:12][CH2:11][CH2:10][C:9]1[CH:4]=[CH:5][C:6]([O:18][CH3:19])=[C:7]([O:16][CH3:17])[CH:8]=1)(=[O:15])[CH3:14]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 21824569N-(6-chloromethyl-3,4-dimethoxyphenethyl)acetamide

Product 1

HCID 80465N-Acetyl-3,4-dimethoxyphenethylamine

Procedure

A sample of this material was recrystallized from ethyl acetate and obtained as clusters of sword-shaped crystals, m.p. 151°-153° dec with evolution of HCl. This substance is the hydrochloride of N-(6-chloromethyl-3,4-dimethoxyphenethyl)acetamide.

Sources & evidence

ORD record: ord-a97c6ff1fbfe4e37bd8973515bb495f3
Source dataset: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04065473

Linked notes

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