HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 2-[2-(1-Piperazinyl)-5-thiadiazolyl]-1-methyl-5-nitroimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| Product | 2-[2-(1-Piperazinyl)-5-thiadiazolyl]-1-methyl-5-nitroimidazole | HCID 21390830 | — |
Reaction Steps
The preparation of the subject compound is carried out essentially as described for the 2-piperidino derivative (Example 28), two equivalents of piperazine replacing the piperidine. The crude project is recrystallized from 2-methoxyethanol to yield the pure compound melting at 240°-241° C. ;cl EXAMPLE 24
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065567 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-12914646f91d4db4b530caf5515c91e9 |
| Source note | uspto-grants-1977_12 |