L-Phenylalanine → Z-Pro-val-OH
Reaction equation
[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:20]([NH:22][C@H:23]([C:31]([OH:33])=[O:32])[CH2:24][C:25]1C=CC=CC=1)=[O:21])[CH2:13][C:14]1[CH:19]=CC=CC=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+]([C:37]1C=CC(OC(=O)[C@H](CC2C=CC=CC=2)NC(OCC2C=CC=CC=2)=O)=CC=1)([O-])=O.N[C@H](C(O)=O)CC1C=CC=CC=1>>[CH2:1]([O:8][C:9]([N:11]1[CH2:19][CH2:14][CH2:13][C@H:12]1[C:20]([NH:22][C@H:23]([C:31]([OH:33])=[O:32])[CH:24]([CH3:25])[CH3:37])=[O:21])=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
4
Procedure
N-benzyloxycarbonyl-L-phenylalanyl-L-phenyl-alanine (m.p. 148°-151° C.) from N-benzyloxycarbonyl-L-phenylalanine 4-nitrophenyl ester and L-phenylalanine.
Sources & evidence
- ORD record
- ord-887bbe60f0224693b11a86a548b58e5c
- Source dataset
- uspto-grants-1992_10