Hydroxyacetone → 2-Propanone, 1-((methylsulfonyl)oxy)-

HRID 47531

Reaction equation

HRID 47531 reaction equation
[OH:1][CH2:2][C:3](=[O:5])[CH3:4].[CH3:6][S:7](Cl)(=[O:9])=[O:8].C(=O)(O)[O-].[Na+]>C(Cl)(Cl)Cl>[CH3:6][S:7]([O:1][CH2:2][C:3]([CH3:4])=[O:5])(=[O:9])=[O:8]

Participants

5

Reactant 3

HCID 8299HydroxyacetoneHCID 31297Methanesulfonyl chlorideHCID 516892Sodium Bicarbonate

Product 1

HCID 1467542-Propanone, 1-((methylsulfonyl)oxy)-

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Thirty-seven (37) mg of hydroxyacetone was dissolved in 2 ml of chloroform, and to which 0.078 ml of methanesulfonyl chloride was added. After stirring the reaction liquid at room temperature for 30 minutes, saturated aqueous sodium bicarbonate solution was added and extracted with chloroform. The extract was dried over anhydrous sodium sulfate and concentrated to provide the title compound.

Workup

  1. customthe reaction liquid at room temperature for 30 minutes
  2. extractionextracted with chloroform
  3. dry with materialThe extract was dried over anhydrous sodium sulfate
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-ae0dc196daec479296ba40aa26395f87
Source dataset
uspto-grants-2004_03
Patent number
US06699880B1

Linked notes

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