2-Fluorophenylhydrazine hydrochloride → 7-Fluoro-1H-indole

HRID 476285

Reaction equation

HRID 476285 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8]N.N[C@H:11]1CN2C3C(C(CC(OCCC)=O)=C2C[CH2:12]1)=CC=CC=3>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:3]=1[NH:8][CH:12]=[CH:11]2

Participants

3

Reactant 2

HCID 4238442-Fluorophenylhydrazine hydrochlorideHCID 58349691(R)-propyl 2-(7-amino-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetate

Product 1

HCID 27745047-Fluoro-1H-indole

Procedure

This compound was prepared from 2-fluoro-phenylhydrazine according to the procedure outlined for propyl ([7R]-7-amino-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetate.

Sources & evidence

ORD record
ord-715286f2f38e4a17b9f2807ad02fe602
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Linked notes

Loading…