1-Pentanol → HCID 19838064, compound
Reaction equation
[OH:1][CH:2]1[NH:6][C:5](=[O:7])[CH:4]=[CH:3]1.[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH3:12]>>[CH2:8]([O:1][CH:2]1[NH:6][C:5](=[O:7])[CH:4]=[CH:3]1)[CH2:9][CH2:10][CH2:11][CH3:12]Participants
3
Conditions
- Temperature
- 50 °C
Procedure
A mixture of 3 g of 1,5-dihydro-5-hydroxy-2H-pyrrol-2-one in 60 cm3 of n-pentyl alcohol and 1.5 g of Amberlite IR 120 H is heated to 50° C. for 3 hours. The temperature is allowed to return to the ambient, and after filtering, the solvent is distilled off under reduced pressure. The residue is distilled at 20° C. under 0.08 mbar. 3.8 g of the expected product is obtained, utilized as it is for the following stage.
Workup
- filtrationafter filtering
- distillationthe solvent is distilled off under reduced pressure
- distillationThe residue is distilled at 20° C. under 0.08 mbar
Sources & evidence
- ORD record
- ord-58280c8a236f4496befb9a8d1a7baa0a
- Source dataset
- uspto-grants-1989_12
- Patent number
- US04885307
Reaction notes
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