Hydrochloric Acid → HCID 178518561, compound

HRID 477750

Reaction equation

HRID 477750 reaction equation
C([O:3][C:4]([N:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[NH:7][C:8]([NH2:10])=[S:9])=O)C.[OH-].[Na+].Cl>O>[OH:3][C:4]1[N:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:7]=[C:8]([SH:9])[N:10]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 857731911-Ethoxycarbonyl-1-phenythiosemicarbazide

Product 1

HCID 178518561HCID 178518561, compoundYield 86.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
25 °C

Procedure

The product of stage (a) (28.9 g) was treated with a solution of sodium hydroxide (7.5 g) in water (150 ml). The suspension was heated under reflux with stirring for 45 minutes and then cooled to 25° C. The pH of the solution was adjusted to 1.0 with concentrated hydrochloric acid and the resulting solid was filtered and washed with water to give 20.2 g of the desired product.

Workup

  1. temperatureThe suspension was heated
  2. temperatureunder reflux
  3. filtrationthe resulting solid was filtered
  4. washwashed with water

Sources & evidence

ORD record
ord-d83609b28ff9451b83aa088a0179c252
Source dataset
uspto-grants-1989_12
Patent number
US04889553

Linked notes

Loading…