Hydroxyamine hydrochloride → 1-(Cyclopropylmethyl)-4-piperidone oxime

HRID 478505

Reaction equation

[CH:1]1([CH2:4][N:5]2[CH2:10][CH2:9][C:8](=O)[CH2:7][CH2:6]2)[CH2:3][CH2:2]1.Cl.[NH2:13][OH:14]>>[CH:1]1([CH2:4][N:5]2[CH2:10][CH2:9][C:8](=[N:13][OH:14])[CH2:7][CH2:6]2)[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 443297Hydroxyamine hydrochloride

HCID 180021811-(Cyclopropylmethyl)piperidin-4-one

Product 1

HCID 180020901-(Cyclopropylmethyl)-4-piperidone oxime

Procedure

1-(Cyclopropylmethyl)-4-piperidone oxime is prepared from 1-(cyclopropylmethyl)-4-piperidone and hydroxylamine hydrochloride essentially as described above in Example 38, Scheme C, step b.

Sources & evidence

ORD record: ord-ccd21a8a1dcd4c74af01cace96da69e8
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06642231B2

Linked notes

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