4-Piperidone → 1-(4-Butoxybutyl)-4-piperidone

Reaction equation

[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][CH2:16][CH3:17]>>[CH2:12]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1)[CH2:11][CH2:10][CH3:9]

Participants

Reactant 2

HCID 337214-Piperidone

HCID 137481391-Butoxy-4-chlorobutane

Product 1

HCID 180020631-(4-Butoxybutyl)-4-piperidone

Procedure

1-(4-Butoxybutyl)-4-piperidone is prepared from 4-piperidone and 1-chloro-4-butoxybutane essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record: ord-8e6b9a60d5654422adcb0788a1ede714
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06642231B2

Reaction notes

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