p-Toluenesulfonic acid → N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-diethyl-4-cyanobutyl]-4-chlorobenzamide

HRID 479513

Reaction equation

HRID 479513 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[N:2]1.[Cl:10][C:11]1[CH:19]=[CH:18][C:14]([C:15]([NH2:17])=[O:16])=[CH:13][CH:12]=1.[C:20]([CH2:22][CH2:23][C:24]([CH2:29][CH3:30])([CH2:27][CH3:28])[CH:25]=O)#[N:21].C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:1]1([CH:25]([NH:17][C:15](=[O:16])[C:14]2[CH:18]=[CH:19][C:11]([Cl:10])=[CH:12][CH:13]=2)[C:24]([CH2:29][CH3:30])([CH2:27][CH3:28])[CH2:23][CH2:22][C:20]#[N:21])[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[N:2]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 120844-ChlorobenzamideHCID 762484-Ethyl-4-formylhexanenitrileHCID 178418385HCID 178418385, compound

Product 1

HCID 18770751N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-diethyl-4-cyanobutyl]-4-chlorobenzamide

Procedure

Benzotriazole, 4-chlorobenzamide, 4-cyano-2,2-diethylbutanal, and p-toluenesulfonic acid were processed as in Example 53A to provide the desired product.

Sources & evidence

ORD record
ord-032416d258a34cf0930a5358ac2bfe91
Source dataset
uspto-grants-2003_11
Patent number
US06645968B2

Linked notes

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