Perfluoropropionyl fluoride → 1,1,1,3,3,4,4,4-Octafluoro-2-(trifluoromethyl)-2-butanol

HRID 483915

Reaction equation

HRID 483915 reaction equation
[F-:1].[K+].[F:3][C:4]([F:12])([C:8]([F:11])([F:10])[F:9])[C:5](F)=[O:6]>C(#N)C>[F:1][C:4]([F:12])([F:3])[C:5]([C:8]([F:11])([F:10])[F:9])([OH:6])[C:4]([F:12])([F:3])[C:8]([F:11])([F:10])[F:9]

Participants

4

Reactant 2

HCID 67912Perfluoropropionyl fluorideHCID 522689Potassium Fluoride

Product 1

HCID 1608131,1,1,3,3,4,4,4-Octafluoro-2-(trifluoromethyl)-2-butanol

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
-196 °C

Procedure

By operating as in the above examples, 0.26 g of KF (4.5 mmol) was charged to the reactor, and then 4.0 ml of anhydrous acetonitrile was injected through the pierceable cap; the whole was then cooled down to -196° C. with the residual air being evacuated; then, 2.0 mmol of pentafluoropropionyl fluoride

Workup

  1. additionwas charged to the reactor
  2. custombeing evacuated

Sources & evidence

ORD record
ord-26b6efaca80344a497d3f837a6d8c214
Source dataset
uspto-grants-1993_07
Patent number
US05227539

Linked notes

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