Chloride → 2-Methyl-3,4,6-trifluorobenzoyl chloride

HRID 486254

Reaction equation

HRID 486254 reaction equation
[CH3:1][C:2]1[C:10]([F:11])=[C:9]([F:12])[CH:8]=[C:7]([F:13])[C:3]=1[C:4](O)=[O:5].[Cl-:14]>>[CH3:1][C:2]1[C:10]([F:11])=[C:9]([F:12])[CH:8]=[C:7]([F:13])[C:3]=1[C:4]([Cl:14])=[O:5]

Participants

3

Reactant 2

HCID 312ChlorideHCID 101303052-Methyl-3,4,6-trifluorobenzoic acid

Product 1

HCID 150076072-Methyl-3,4,6-trifluorobenzoyl chloride

Procedure

To 2-methyl-3,4,6-trifluorobenzoic acid (3.2 g) is added thiony chloride (7 ml) and the mixture is refluxed for hour. After concentrating, 2-methyl-3,4,6-trifluorobenzoyl chloride (3.3 g) is obtained.

Workup

  1. temperaturethe mixture is refluxed for hour
  2. concentrationAfter concentrating

Sources & evidence

ORD record
ord-2df2766700ed406bba7639e5b14b0a74
Source dataset
uspto-grants-1994_03
Patent number
US05290934

Linked notes

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