Pyridine → 1-(2-Methoxy-2-oxoethyl)pyridinium chloride
Reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:7][CH2:8][C:9]([O:11][CH3:12])=[O:10]>C(OCC)(=O)C>[Cl-:7].[CH3:12][O:11][C:9]([CH2:8][N+:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:10]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Pyridine (1 equivalent) and methyl chloroacetate (1 equivalent) in ethyl acetate were heated (80° C.) for 24 hours. The reaction mixture was cooled to room temperature and the resulting crystalline pyridinium salt filtered, washed with ethyl acetate, and dried in vacuum.
Workup
- filtrationthe resulting crystalline pyridinium salt filtered
- washwashed with ethyl acetate
- customdried in vacuum
Sources & evidence
- ORD record
- ord-d6f60419ed23424aa2a11487ac3fbb00
- Source dataset
- uspto-grants-1994_03
- Patent number
- US05294721
Reaction notes
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